The Andersonville National Historic Site, located near Andersonville, Georgia, preserves the former Andersonville Prison (also known as Camp Sumter), a Confederate prisoner-of-war camp during the final fourteen months of the American Civil War. Most of the site lies in southwestern Macon County, adjacent to the east side of the town of Andersonville. The site also contains the Andersonville National Cemetery and the National Prisoner of War Museum. The prison was created in February 1864 and served until April 1865.

The site was commanded by Captain Henry Wirz, who was tried and executed after the war for war crimes. The prison was overcrowded to four times its capacity, and had an inadequate water supply, inadequate food, and unsanitary conditions. Of the approximately 45,000 Union prisoners held at Camp Sumter during the war, nearly 13,000 (28%) died. The chief causes of death were scurvy, diarrhea and dysentery.